deactivate_plugins( string|string[] $plugins, bool $silent = false, bool|null $network_wide = null )

function deactivate_plugins( $plugins, $silent = false, $network_wide = null ) {
	if ( is_multisite() )
		$network_current = get_site_option( 'active_sitewide_plugins', array() );
	$current = get_option( 'active_plugins', array() );
	$do_blog = $do_network = false;

	foreach ( (array) $plugins as $plugin ) {
		$plugin = plugin_basename( trim( $plugin ) );
		if ( ! is_plugin_active($plugin) )
			continue;

		$network_deactivating = false !== $network_wide && is_plugin_active_for_network( $plugin );

		if ( ! $silent ) {
			/**
			 * Fires before a plugin is deactivated.
			 *
			 * If a plugin is silently deactivated (such as during an update),
			 * this hook does not fire.
			 *
			 * @since WP-2.9.0
			 *
			 * @param string $plugin               Path to the main plugin file from plugins directory.
			 * @param bool   $network_deactivating Whether the plugin is deactivated for all sites in the network
			 *                                     or just the current site. Multisite only. Default is false.
			 */
			do_action( 'deactivate_plugin', $plugin, $network_deactivating );
		}

		if ( false !== $network_wide ) {
			if ( is_plugin_active_for_network( $plugin ) ) {
				$do_network = true;
				unset( $network_current[ $plugin ] );
			} elseif ( $network_wide ) {
				continue;
			}
		}

		if ( true !== $network_wide ) {
			$key = array_search( $plugin, $current );
			if ( false !== $key ) {
				$do_blog = true;
				unset( $current[ $key ] );
			}
		}

		if ( ! $silent ) {
			/**
			 * Fires as a specific plugin is being deactivated.
			 *
			 * This hook is the "deactivation" hook used internally by register_deactivation_hook().
			 * The dynamic portion of the hook name, `$plugin`, refers to the plugin basename.
			 *
			 * If a plugin is silently deactivated (such as during an update), this hook does not fire.
			 *
			 * @since WP-2.0.0
			 *
			 * @param bool $network_deactivating Whether the plugin is deactivated for all sites in the network
			 *                                   or just the current site. Multisite only. Default is false.
			 */
			do_action( "deactivate_{$plugin}", $network_deactivating );

			/**
			 * Fires after a plugin is deactivated.
			 *
			 * If a plugin is silently deactivated (such as during an update),
			 * this hook does not fire.
			 *
			 * @since WP-2.9.0
			 *
			 * @param string $plugin               Path to the main plugin file from plugins directory.
			 * @param bool   $network_deactivating Whether the plugin is deactivated for all sites in the network.
			 *                                     or just the current site. Multisite only. Default false.
			 */
			do_action( 'deactivated_plugin', $plugin, $network_deactivating );
		}
	}

	if ( $do_blog )
		update_option('active_plugins', $current);
	if ( $do_network )
		update_site_option( 'active_sitewide_plugins', $network_current );
}